- Globular proteins are roughly spherical biomolecules with attractive, and highly directional interactions. This microscopic observation motivates describing these proteins as patchy particles: hard spheres with attractive surface patches. Mapping a biomolecule to a patchy model requires simplifying effective protein-protein interactions, which in turn provides a microscopic understanding of the protein solution behavior. The patchy model can indeed be fully analyzed, including its phase diagram. In this chapter, we detail the methodology of mapping a given protein to a patchy model and of determining the phase diagram of the latter. We also briefly describe the theory upon which the methodology is based, provide practical information, and discuss ... [Read More]
- Total Size
- 2 files (207 KB)
- Data Citation
- Altan, I., & Charbonneau, P. (2019). Data and scripts from: Obtaining soft matter models of proteins and their phase behavior. Duke Digital Repository. https://doi.org/10.7924/r4ww7bs1p
- Creator
- DOI
- 10.7924/r4ww7bs1p
- Publication Date
- February 4, 2019
- ARK
- ark:/87924/r4ww7bs1p
- Contributor
- Publisher
- Type
- Contact
- Irem Altan: irem.altan@duke.edu, ORCID: 0000-0001-9303-9104
- Title
- Data and scripts from: Obtaining soft matter models of proteins and their phase behavior
- Repository
| Thumbnail | Title | Date Uploaded | Actions | |
|---|---|---|---|---|
|
README.txt | 2019-02-04 | Download | |
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data_and_scripts.zip | 2019-02-05 | Download |