GENERAL INFORMATION 1. Title of Dataset: Mutual Information: Measuring Nonlinear Dependence in Longitudinal Epidemiological Data 2. Author Information A. Contact Information Name: Duke Research Respository Institution: Duke University Email: anesresearchdatasvc@duke.edu 3. Date of data collection: 1999-01-01 to 2003-12-31 4. Geographic location of data collection: Durham, NC 5. Information about funding sources that supported the collection of the data: None SHARING/ACCESS INFORMATION 1. Licenses/restrictions placed on the data: Creative Commons Zero (CC0) 6. Recommended citation for this dataset: pending DATA & FILE OVERVIEW 1. File List: 2907 DataFile 1(through 21) designate each file. Files are identical in structure and can be sorted by Case_ID to identify all data related to a single patient. File Name file type # rows 2907 Data File 1 .xls 1,000,000 2907 Data File 2 .xls 1,000,000 2907 Data File 3 .xls 1,000,000 2907 Data File 4 .xls 1,000,000 2907 Data File 5 .xls 1,000,000 2907 Data File 6 .xls 1,000,000 2907 Data File 7 .xls 1,000,000 2907 Data File 8 .xls 1,000,000 2907 Data File 9 .xls 1,000,000 2907 Data File 10 .xls 1,000,000 2907 Data File 11 .xls 1,000,000 2907 Data File 12 .xls 1,000,000 2907 Data File 13 .xls 1,000,000 2907 Data File 14 .xls 1,000,000 2907 Data File 15 .xls 1,000,000 2907 Data File 16 .xls 1,000,000 2907 Data File 17 .xls 1,000,000 2907 Data File 18 .xls 1,000,000 2907 Data File 19 .xls 1,000,000 2907 Data File 20 .xls 1,000,000 2907 Data File 21 .xls 734,987 2. Relationship between files, if important: there is no specific relationship between the files. If appended together, there should be no duplication of rows. 3. Are there multiple versions of the dataset? no METHODOLOGICAL INFORMATION 1. Description of methods used for collection/generation of data: Query of clinical database for all procedures during the relevant time period. 2. Methods for processing the data: analysis and data preparation details are described in publication. 3. Instrument- or software-specific information needed to interpret the data: none 4. Standards and calibration information, if appropriate: n/a 5. Environmental/experimental conditions: n/a 6. Describe any quality-assurance procedures performed on the data: please reference publication for details. 7. People involved with sample collection, processing, analysis and/or submission: Alexander young, Willem van den Boom, Rebecca Schroeder, Vijay Krishnamoorthy, Karthik Raghunathan, Hau-Tieng Wu, David Dunson DATA-SPECIFIC INFORMATION FOR: 2907 Innovian Vital Data 1 (repeated for 2-22) 1. Number of variables: 8 2. Number of cases/rows: 20,734,986 3. Variable List: • Case_ID: Variable containing a deidentified ID for each unique case within the Innovian database • Age_Years: Variable containing a decimal value specifying the patient's age at time of surgery • ASAStatusName: Variable containing ASA value for the patient corresponding to the relevant case; Codes found here: https://www.asahq.org/standards-and-guidelines/asa-physical-status-classification-system [1, 2, 3, 4, 5] • ASA_E: Variable indicating the ASA emergent status for the patient corresponding to the relevant case; 0 = non emergency, 1 = emergency • CPB_In_Case: Variable indicator of usage of cardiopulmonary bypass in case, used to detect cardiac cases; 1=cardiac case, 0= noncardiac case • VitalParameterName: Variable containing the name of the vital parameter name corresponding to the upcoming values and timestamp CVP1 Mean mean central venous pressure PA1 Dias diastolic pulmonary artery blood pressure PA1 Sys systolic pulmonary artery blood pressure Art1 Dias diastolic arterial blood pressure Art1 Sys systolic arterial blood pressure Art1 Mean mean arterial blood pressure PA1 Mean mean pulmonary artery blood pressure NIBP Sys systolic noninvasive blood pressure NIBP Dias diastolic noninvasive blood pressure NIBP Mean mean noninvasive blood pressure NIBP diastolic_ diastolic noninvasive blood pressure NIBP - systolic_ systolic noninvasive blood pressure Arterial BP diastolic_ diastolic arterial blood pressure Arterial BP - Systolic_ systolic arterial blood pressure Arterial BP - mean_ mean arterial blood pressure PA Mean mean pulmonary artery blood pressure CVP Mean mean central venous pressure ABP Mean mean arterial blood pressure ABP Dias diastolic arterial blood pressure ABP Sys systolic arterial blood pressure PA Dias diastolic pulmonary artery blood pressure PA Sys systolic pulmonary artery blood pressure NIBP Pulse noninvasive blood pressure-derived pulse rate • Vital_Value: Variable containing the value of the vital specified previously, the value's units are dependent on the specific vital type • Vital_Timestamp: Variable containing the timestamp at which the previous value occurred during the specified case; dates have been shifted by an unspecified number of days to mask PHI. 4. Missing data codes: none 5. Specialized formats or other abbreviations used: ASA = American Society of Anesthesiologists Physical Status, CPB = cardiopulmonary bypass