Multi-region local field potential recordings during a tail-suspension test

• We collected a dataset of LFPs recorded from 26 mice from two different genetic backgrounds (14 wild type, 12 CLOCK Delta-19). The CLOCK Delta-19 line of mice have been proposed as a model of bipolar disorder . There are 20 minutes of recordings for each mouse: 5 minutes while the mouse was in its home cage, 5 minutes during open field exploration, and 10 minutes during a tail suspension test. The tail suspension test is used as an assay of response to a challenging experience. Eleven distinct brain regions were recorded: Nucleus Accumbens Core, Nucleus Accumbens Shell, Basolateral Amygdala, Infralimbic Cortex, Mediodorsal Thalamus, Prelimbic Cortex, Ventral Tegmental Area, Lateral Dorsal Hippocampus, Lateral Substantia Nigra Pars Compacta, Medial Dorsal Hippocampus, and Medial Substantia Nigra Pars Compacta. ... [Read More]

Total Size

120 files (11.2 GB)

Data Citation

• Carlson, D., Kumar, S., & Dzirasa, K. (2023). Multi-region local field potential recordings during a tail-suspension test. Duke Research Data Repository. https://doi.org/10.7924/r4q52sj36

Creator

• Kumar, Sunil
• Carlson, David
• Dzirasa, Kafui

DOI

• 10.7924/r4q52sj36

Subject

• Local field potentials
• Bipolar mouse model
• Tail suspension test
• Electrical functional connectome

Publication Date

• March 14, 2023

ARK

• ark:/87924/r4q52sj36

Affiliation

• Biostatistics and Bioinformatics
• Psychiatry and Behavioral Sciences
• Howard Hughes Medical Institute

Publisher

• Duke Research Data Repository

Type

• Dataset

Format

• MAT

Related Materials

• Carlson, David, et al. (2017). Dynamically timed stimulation of corticolimbic circuitry activates a stress-compensatory pathway. Biological psychiatry 82.12: 904-913.  https://doi.org/10.1016/j.biopsych.2017.06.008
• Gallagher, Neil, et al. (2017). Cross-spectral factor analysis. Advances in neural information processing systems 30. ISBN: 9781510860964

Funding Agency

• National Institute of Mental Health

Grant Number

• R01MH099192

Contact

• David Carlson: david.carlson@duke.edu, https://orcid.org/0000-0003-1005-6385

License

• Creative Commons BY-NC Attribution-NonCommercial 4.0 International

Title

• Multi-region local field potential recordings during a tail-suspension test

License

• https://creativecommons.org/licenses/by-nc/4.0/

Repository

• Duke Research Data Repository