- GWAS summary statistics for Y. pestis invasion in 961 LCLs generated using QFAM-parents in PLINK with adaptive permutation. For details of methods refer to manuscript Keener et al. 2024.
Yersinia pestis is the gram-negative bacterium responsible for plague, one of the deadliest and most feared diseases in human history. This bacterium is known to infect phagocytic cells, such as dendritic cells and macrophages, but interactions with non-phagocytic cells of the adaptive immune system are frequently overlooked despite the importance they likely hold for human infection. To discover human genetic determinants of Y. pestis infection, we utilized nearly a thousand genetically diverse lymphoblastoid cell lines in a ... [Read More]
- Total Size
- 2 files (1.01 GB)
- Data Citation
- Keener, R., Wang, L., & Ko, D. (2024). Data from: Human genetic variation reveals FCRL3 is a lymphocyte receptor for Yersinia pestis. Duke Research Data Repository. https://doi.org/10.7924/r43n2d008
- DOI
- 10.7924/r43n2d008
- Publication Date
- December 13, 2024
- ARK
- ark:/87924/r43n2d008
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- Title
- Data from: Human genetic variation reveals FCRL3 is a lymphocyte receptor for Yersinia pestis
- Repository
Thumbnail | Title | Date Uploaded | Visibility | Actions |
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KeenerKo_DATASET_Readme.txt | 2024-12-13 | Download | |
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KeenerKo_HH3_SummaryStats_Ypestis4hrstringent.txt | 2024-12-13 | Download |